Ongoing Projects

DeepBIOHM: Enhancing BIOHM DataMap Platform Using Deep Learning (Virginia Tech (Xuan) and BIOHM (Schatz & Khater)

Deep Machine Learning for Financial Market Forcasting/Prediction (Virginia Tech (Xuan))

Neuro-inspired Deep Models for Human Visual Systems & Computer Vision

Deep Reinforcement Learning Algorithms with Their Applications in Robotics (Virginia Tech (Xuan))

Deep Machine Learning to Predict Protein Functions (Virginia Tech (Xuan) and University of Maryland School of Medicine (Neuwald))

Neuro-inspired Deep Learning Algorithms and Systems with Their Applications in Biomedical Research (Virginia Tech (Xuan))

Completed Projects

Uncovering Estrogen Receptor-Signaling Networks to Overcome Endocrine Resistance (NIH/NCI R01CA149653) (PI, Xuan, Virginia Tech; Co-PI, Clarke, Georgetown University)

Network-based Prediction of Antiestrogen Resistance in Breast Cancer (NIH/NCI R21CA139246) (PI, Xuan, Virginia Tech; Co-PI, Clarke, Georgetown University)

Transgenerational Effects of Maternal High Fat Diet During Pregnancy of Breast Cancer (NIH/NCI R01CA164384) (PI, Hilakivi-Clarke, Georgetown University; Co-PI, Xuan, Virginia Tech)

Collaborative Research In Integrative Cancer Biology (NIH/NCI U01CA184902) (PI, Clarke, Georgetown University; Co-PI, Wang, Virginia Tech (Co-I, Xuan))

Early Detection of Ovarian Cancer with Special Focus on BRCA Carrier (Gray Foundation) (PI: Shih, JHU; PI of the Subaward to VT: Xuan, Virginia Tech)

Center for Cancer Systems Biology: Integration of ER-related Signaling in Breast Cancer (NIH/NCI U54CA149147) (PI: Clarke, Georgetown University; Co-PI, Wang, Virginia Tech (Co-I, Xuan); Fox Chase Cancer Center)

Endocrine Therapy of Breast Cancer (DOD/CDMRP BC030280) (PI: Clarke, Georgetown University; Co-PI, Xuan, Virginia Tech)

Improved Diagnostics of the Muscular Dystrophies (NIH/NINDS R01NS29525-18A1 & 13A1) (PI, Hoffman, Children’s National Medical Center; Co-PIs, Xuan & Wang, Virginia Tech)

Polarization Cellular Imaging and Diagnosis (NASA NNJ05JC13C) (PI, Zhou, BATi ; Co-PI, Xuan, Virginia Tech)

Proteome Characterization Center: A Genoproteomics Pipeline for Cancer Biomarkers (NIH/NCI-CPTC U24CA160036) (Johns Hopkins Medical Institutions; Virginia Tech (Co-I, Xuan); Stanford U.; Memorial Sloan-Kettering Cancer Center; M.D. Anderson Cancer Center; U of Chicago)

Genomic and Proteomic Architecture of Atherosclerosis (NIH/NHLBI R01HL111362) (PI, Herrington, Wake Forest U; Co-PI, Wang, Virginia Tech (Co-I, Xuan); Johns Hopkins U, MIT)

caBIG In Silico Research Centers of Excellence (PI, Clarke, Georgetown University; Co-PI, Wang, Virginia Tech (Co-I, Xuan))

Comprehensive Analysis of Microarray Gene Expression Data (NIH/NCI CA109872) (Co-I, Xuan)

Bioengineering Research Partnerships: Molecular Analysis of Human Breast Cancer (NIH/NCI CA096483) (Co-I, Xuan)

Center of Excellence: Molecular Epidemiology and Mechanisms for Breast Carcinogenesis    (DOD/CDMRP DAMD17-03-1-0448) (Co-I, Xuan)

Computational Decomposition of Composite Molecular Signatures (NIH/NIBIB EB000830) (Co-I, Xuan)

Center of Excellence: Timing of Dietary Exposure and Breast Cancer Risk (NIH/NCI CA100970) (Co-I, Xuan)

Statistical Visualization of Localized Prostate Cancer (NIH RR12784) (Co-I, Xuan)